Nobel Prize in Medicine winners announced - Brunkow, Ramsdell and Sakaguchi for "discoveries in peripheral immune tolerance"
Scientists Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi won the 2025 Nobel Prize in Physiology or Medicine for "their discoveries concerning peripheral immune tolerance".
This year's award is related to how we keep our immune system in check so that we can fight off all imaginable microbes and avoid autoimmune diseases.
The medicine laureates are chosen by the Nobel Assembly at Sweden's Karolinska Institutet medical university and receive a prize of 11 million Swedish kronor ($1.2 million), as well as a gold medal presented by the King of Sweden.
Brunkow and Ramsdell are based in the United States, and Sakaguchi in Japan.
"Their discoveries have laid the foundations for a new field of research and have spurred the development of new treatments, for example for cancer and autoimmune diseases," the awards body said in a statement.
The Nobel Prizes were established by the will of Alfred Nobel, the Swedish inventor of dynamite and a wealthy businessman. They have been awarded since 1901 for outstanding contributions to science, literature and peace, with interruptions mainly during the World Wars.
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